PROTAC CBP/P300 Degrader-4 is a p300/CBP PROTAC degrader with DC50 of 17.4 nM and 10.2 nM against p300 and CBP in U2OS cells, respectively. PROTAC CBP/P300 Degrader-4 forms ternary complexes with p300 or CBP and an E3 ligase, drives ubiquitination, and mediates proteasomal degradation. PROTAC CBP/P300 Degrader-4 can be used for the research of hematological malignancies[1].
Molecular Weight:
962.05
Formula:
C50H57F2N11O7
Target:
Histone Acetyltransferase,PROTACs
Application Notes:
MCE Product type: Reference compound
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