IRE1alpha kinase-IN-2 is a potent IRE1alpha kinase inhibitor, with an EC50 of 0.82 µM. IRE1alpha kinase-IN-2 inhibits IRE1alpha kinase autophosphorylation (IC50=3.12 µM). IRE1alpha kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines[1].
Molecular Weight:
504.51
Purity:
99.24
CAS Number:
[1414938-21-8]
Formula:
C27H23F3N6O
Target:
IRE1
Application Notes:
MCE Product type: Reference compound
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