EphB4-IN-1, CAS [[1394837-94-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-185227
Supplier Catalog Number:
HY-185227
Alternative Catalog Number:
MCE-HY-185227-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
EphB4-IN-1 is a selective EphB4 tyrosine kinase inhibitor with IC50 values of 0.16-0.30 µM. EphB4-IN-1 binds to the ATP binding site of EphB4 in a DFG-in conformation, forming four stable intermolecular hydrogen bonds. EphB4-IN-1 also inhibits Src, Abl1, Lck, and EGFR kinases. EphB4-IN-1 inhibits EphB4 autophosphorylation. EphB4-IN-1 can be used for the research of cancer, such as non small cell lung cancer[1].
Molecular Weight:
322.36
CAS Number:
[1394837-94-5]
Formula:
C18H18N4O2
Target:
Bcr-Abl,EGFR,Ephrin Receptor,Src
Application Notes:
MCE Product type: Reference compound
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