EGFR-IN-204 (Example 1) is a HER2 exon 20 mutation inhibitor with selectivity for wild-type EGFR. EGFR-IN-204 exerts antiproliferative effects on cells dependent on HER2 exon 20 YVMA insertion mutation and wild-type HER2, and shows strong selectivity over cells dependent on wild-type EGFR. EGFR-IN-204 is applicable to non-small cell lung cancer research[1].
Molecular Weight:
565.60
Purity:
98.57
CAS Number:
[2989904-86-9]
Formula:
C31H28FN7O3
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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