Gem-C12 is a prodrug of Gemcitabine (HY-17026). Gem-C12 terminates DNA chain elongation, inhibits nucleic acid synthesis and induces Apoptosis. Gem-C12 inhibits the proliferation of glioma cells. Gem-C12 and Honokiol (HY-N0003) exhibit synergistic anti-glioblastoma activity. Gem-C12 can be used in research related to glioblastoma multiforme[1].
Molecular Weight:
445.50
Purity:
98.02
CAS Number:
[849139-19-1]
Formula:
C21H33F2N3O5
Target:
Apoptosis,DNA/RNA Synthesis,Drug Derivative
Application Notes:
MCE Product type: Reference compound
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