RMC-9945 (RM-044) is a KRAS inhibitor and selective, covalent, orally active RAS(ON) G12D inhibitor. RMC-9945 increases beta-Catenin/TCF transcriptional activity. RMC-9945 exerts durable disease control in preclinical colorectal cancer models of early liver metastasis[1][2].
Molecular Weight:
1140.41
CAS Number:
[2922732-38-3]
Formula:
C60H80F3N11O6S
Target:
Ras,beta-catenin
Application Notes:
MCE Product type: Reference compound
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