4-M-HMBPP is a weak agonist for Vgamma9Vdelta2 T cell activation and a potent competitive inhibitor of HMBPP. 4-M-HMBPP binds to BTN3A1 with high affinity (KD: 26.2 µM), but fails to induce its complex formation with BTN2A1. 4-M-HMBPP can be used in studies on gammadelta T cell activation[1].
Molecular Weight:
406.19
Formula:
C12H15F3O8P2
Target:
Nuclear Factor of activated T Cells (NFAT)
Application Notes:
MCE Product type: Reference compound
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