AcdK is a non-natural amino acid and a precursor of allysine. AcdK allows site-specific incorporation into target proteins in E. coli via the amber suppression strategy. AcdK enables site-specific lysine dimethylation or monomethylation modification of target proteins. AcdK can synthesize site-specific lysine-methylated variants of histone H3 and p53, which is applicable for investigating the substrate specificity and catalytic function of epigenetic enzymes[1].
Molecular Weight:
319.32
CAS Number:
[2097535-26-5]
Formula:
C14H17N5O4
Target:
Amino Acid Derivatives
Application Notes:
MCE Product type: Reference compound
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