SHP1-IN-2 is a selective and orally active SHP1 inhibitor. SHP1-IN-2 covalently binds to Cys480 of SHP1. SHP1-IN-2 elicits potent antitumor immunity and suppresses syngeneic tumor growth. SHP1-IN-2 blocks tumor progression in a svngeneic cancer model by activating natural killer cells and cytotoxic CD8+ T cells, along with reduced T cel l. SHP1-IN-2 can be used for cancer-related research[1].
Molecular Weight:
355.82
Formula:
C13H10ClN3O3S2
Target:
ERK,Interleukin Related,Phospholipase,SHP1
Application Notes:
MCE Product type: Reference compound
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