NK 314 is an inhibitor for topoisomerase IIalpha, which generates the break of DNA double-strand. NK 314 arrests the cell cycle at G2 phase in human acute myeloid leukemia cells, inhibits the proliferation of CEM with IC90 of 55 nM[1].
Molecular Weight:
395.84
CAS Number:
[208237-49-4]
Formula:
C22H18ClNO4
Target:
Topoisomerase
Application Notes:
MCE Product type: Reference compound
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