CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1-hydroxylase activity are 0.03 µM, 17 µM, and 71 µM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism[1].
Molecular Weight:
456.59
Purity:
99.92
CAS Number:
[1390637-82-7]
Formula:
C26H32N8
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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