Galidesivir (BCX4430) hydrochloride, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir hydrochloride is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir hydrochloride inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 µM[1][2][3].
Molecular Weight:
301.73
Purity:
99.89
CAS Number:
[222631-44-9]
Formula:
C11H16ClN5O3
Target:
DNA/RNA Synthesis,Filovirus,SARS-CoV
Application Notes:
MCE Product type: Reference compound
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