Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay. Target: Mutant IDH1 Mutant IDH1-IN-2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer. More bioactivity information in Patent WO 2013046136A1 (Example 224).
Molecular Weight:
459.53
Purity:
98.50
CAS Number:
[1429176-69-1]
Formula:
C24H31F2N5O2
Target:
Isocitrate Dehydrogenase (IDH)
Application Notes:
MCE Product type: Reference compound1
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