Endoxifen Z-isomer is an oral active Tamoxifen (HY-13757A) metabolite, inducing an anti-estrogenic effect in breast cancer cells expressing ERalpha. Endoxifen Z-isomer inhibits hERG. This effect is concentration-dependent, with an IC50 value of 1.6 µM[1][2][3][4].
Molecular Weight:
373.49
Purity:
99.19
CAS Number:
[112093-28-4]
Formula:
C25H27NO2
Target:
Estrogen Receptor/ERR,Potassium Channel
Application Notes:
MCE Product type: Reference compound1
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