Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation[1][2][3].
Molecular Weight:
355.27
Purity:
99.97
CAS Number:
[448947-81-7]
Formula:
C13H8Cl2N4S2
Target:
Akt,ERK,Piezo Channel,Potassium Channel
Application Notes:
MCE Product type: Reference compound
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