L-NAME inhibits NOS with an IC50 of 70 µM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 µM. L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME can be used to induce hypertension and preeclampsia models.
Molecular Weight:
233.23
CAS Number:
[50903-99-6]
Formula:
C7H15N5O4
Target:
NO Synthase
Application Notes:
MCE Product type: Reference compound
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