AFG210 is a potent multi-target kinase inhibitor that primarily inhibits Abl kinase (IC50=330 nM), and also has inhibitory effects on other kinases such as B-Raf, C-Raf, FGFR-1, RET and VEGF receptors. AFG210 can be used to study chronic myeloid leukemia and other diseases with abnormal activation of Abl kinase[1].
Molecular Weight:
373.33
CAS Number:
[228400-22-4]
Formula:
C19H14F3N3O2
Target:
Bcr-Abl,FGFR,Raf,RET,VEGFR
Application Notes:
MCE Product type: Reference compound1
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