CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-kappaB and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis[1].
Molecular Weight:
336.43
Purity:
99.73
CAS Number:
[1197996-80-7]
Formula:
C21H24N2O2
Target:
Histone Acetyltransferase,MDM-2/p53,NF-kappaB
Application Notes:
MCE Product type: Reference compound1
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