Siguazodan (SKF 94836) is a potent, selective and orally active phosphodiesterase III (PDE-III) inhibitor with an IC50 of 117 nM. Siguazodan increases cAMP accumulation in intact platelets with an EC50 of 18.88 µM. Siguazodan also inhibits phenylephrine-induced 5-HT release with an IC50 value of 4.2 µM[1][2][3].
Molecular Weight:
284.32
Purity:
99.06
CAS Number:
[115344-47-3]
Formula:
C14H16N6O
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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