CI-959 is an inhibitor of inflammatory cell activation. CI-959 exhibits anti-inflammatory and anti-allergic activities. CI-959 can inhibit the production of reactive oxygen species by neutrophils, as well as neutrophil adhesion, respiratory burst, and histamine release from mast cells. CI-959 can also inhibit the release of inflammatory mediators such as histamine, leukotrienes, and thromboxane from guinea-pig and human lung tissues, and effectively suppress anti-IgE-induced contractions of human bronchial smooth muscle. CI-959 can be used in the research of inflammatory and allergic diseases, such as asthma[1][2][3].
Molecular Weight:
356.36
CAS Number:
[104795-68-8]
Formula:
C14H15N5NaO3S
Target:
Histamine Receptor,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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