ME-3407 (EF-4040) is a H+-K+-ATPase redistribution disruptor and myosin light chain kinase (MLCK) and protein kinase A inhibitor. ME-3407 blocks gastric acid secretion and aminopyrine accumulation by inhibiting microsomal-to-apical membrane redistribution of H+-K+-ATPase and suppressing MLCK-mediated myosin light chain phosphorylation. ME-3407 is promising for research of peptic ulcer[1].
Molecular Weight:
298.38
CAS Number:
[133903-90-9]
Formula:
C12H14N2O3S2
Target:
Myosin,Na+/K+ ATPase,PKA
Application Notes:
MCE Product type: Reference compound
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