SR 47063 is an ATP-sensitive potassium channel (KATP) agonist. SR 47063 selectively activates KATP channels in vascular smooth muscle cells (IC50: 8.1 nM in human saphenous vein, 3.86 nM in rat aorta). SR 47063 promotes potassium efflux and cellular hyperpolarization to induce vasorelaxation. SR 4706 is promising for research of hypertension and related cardiovascular disorders[1].
Molecular Weight:
322.32
CAS Number:
[135809-60-8]
Formula:
C17H14N4O3
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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