CJ-12255 is a selective NK1-R antagonist. CJ-12255 has no affinity for the NK-2 or NK-3 receptors. CJ-12255 blocks an substance P (SP)-induced chronic ulcerative colitis (CUC) in rats. CJ-12255 also reduces intraabdominal adhesion formation during abdominal surgery in rats[1][2].
Molecular Weight:
498.66
CAS Number:
[146725-78-2]
Formula:
C32H38N2O3
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound1
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