PD-143188 (CI 1007) is a selective agonist targeting dopamine (DA) receptors, with Ki values of 25.5 nM and 16.6 nM for human D2 and D3 receptors, respectively and lower affinity for D4.2 receptors (Ki=90.9 nM). PD-143188 inhibits DA release, synthesis and metabolism, while reducing cellular cyclic AMP levels, exerting antipsychotic activity. PD-143188 is promising for research of psychopharmacology[1].
Molecular Weight:
329.48
CAS Number:
[150013-70-0]
Formula:
C24H27N
Target:
Dopamine Receptor
Application Notes:
MCE Product type: Reference compound1
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