S-18326 is an orally active direct thrombin inhibitor. S-18326 inhibits thrombus formation by reversibly and with high affinity binding to the active site of thrombin, directly preventing the conversion of fibrinogen to fibrin. S-18326 effectively prolongs various clotting times in human plasma. S-18326 has demonstrated antithrombotic efficacy in multiple animal models without causing thrombocytopenia. S-18326 can be used in research on thromboembolic diseases[1].
Molecular Weight:
488.39
CAS Number:
[167843-21-2]
Formula:
C23H37BN6O5
Target:
Thrombin
Application Notes:
MCE Product type: Reference compound
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