PIM447 (LGH447) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis[1][2].
Molecular Weight:
440.46
Purity:
99.52
CAS Number:
[1210608-43-7]
Formula:
C24H23F3N4O
Target:
Apoptosis,Pim
Application Notes:
MCE Product type: Reference compound1
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