PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis[1][2].
Molecular Weight:
513.38
Purity:
99.94
CAS Number:
[1820565-69-2]
Formula:
C24H25Cl2F3N4O
Target:
Apoptosis,Pim
Application Notes:
MCE Product type: Reference compound1
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