TMS ((E)-2,3,4,5-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC50 of 6 nM and a Ki value of 3 nM. TMS shows a lesser extent inhibitory effect on CYP1A1 (IC50=300 nM) and CYP1A2 (IC50=3.1 µM). TMS is a methylated derivative of resveratrol and has anti-cancer activity[1][2][3].
Molecular Weight:
300.35
Purity:
99.40
CAS Number:
[24144-92-1]
Formula:
C18H20O4
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound1
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