Vacquinol-1 (NSC13316) is a MKK4-specific activator that activates MAPK pathways[1]. Vacquinol-1 specifically induces human glioblastoma cell (GC) death, attenuates tumor progression and prolongs survival in a glioblastoma multiforme (GBM) mouse model[2]. Vacquinol-1 also induces apoptosis in hepatocellular carcinoma (HCC)cell[3].
Molecular Weight:
352.86
CAS Number:
[5428-80-8]
Formula:
C21H21ClN2O
Target:
p38 MAPK
Application Notes:
MCE Product type: Reference compound
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