RGFA-8, TC-H 106, Histone Deacetylase Inhibitor VII
Pimelic Diphenylamide 106 (TC-H 106) is a slow, tight binding class I HDAC inhibitor (inhibits HDAC1, 2, and 3 with IC50 values of 150 nM, 760 nM, and 370 nM, respectively), with no activity against class II HDACs. Pimelic Diphenylamide 106 modulates dopamine concentration and protects dopamine cells by inducing VMAT2 expression. Pimelic Diphenylamide 106 can be used in the study of neuropsychiatric diseases such as attention deficit hyperactivity disorder (ADHD)[1][2][3].
Molecular Weight:
339.43
Purity:
98.54
CAS Number:
[937039-45-7]
Formula:
C20H25N3O2
Target:
HDAC,Monoamine Transporter
Application Notes:
MCE Product type: Reference compound
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