Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-kappaB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia[1][2][3].
Molecular Weight:
505.56
Purity:
99.34
CAS Number:
[84573-16-0]
Formula:
C29H31NO7
Target:
Eukaryotic Initiation Factor (eIF),HSP,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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