Didesmethylrocaglamide, a derivative of Rocaglamide, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. Didesmethylrocaglamide has potent growth-inhibitory activity with an IC50 of 5 nM. Didesmethylrocaglamide suppresses multiple growth-promoting signaling pathways and induces apoptosis in tumor cells. Antitumor activity[1][2].
Molecular Weight:
477.51
Purity:
98.84
CAS Number:
[177262-30-5]
Formula:
C27H27NO7
Target:
Apoptosis,Eukaryotic Initiation Factor (eIF)
Application Notes:
MCE Product type: Reference compound
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