Ro-65-2299 is an orally active retiferol Vitamin D analogue and a potential VDR agonist (ED50 = 180 nM). Ro-65-2299 can induce thickening of the epidermis and exhibits antipsoriatic effect in hairless mice (ED50 = 7.5 mg/kg). Ro-65-2299 can be used for the researches of inflammation and immunology, such as psoriasis[1].
Molecular Weight:
444.45
CAS Number:
[241151-12-2]
Formula:
C21H30F6O3
Target:
Drug Derivative,VD/VDR
Application Notes:
MCE Product type: Reference compound1
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