Ro 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. Ro 46-8443 displays an at least 100-fold selectivity for ETB (IC50: 34-69 nM) over ETA receptors (IC50: 6800 nM)[1][2].
Molecular Weight:
609.69
Purity:
98.93
CAS Number:
[175556-12-4]
Formula:
C31H35N3O8S
Target:
Endothelin Receptor
Application Notes:
MCE Product type: Reference compound
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