UCB-35440 is an orally active histamine H1 receptor antagonist and 5-lipoxygenase inhibitor. UCB-35440 inhibits LTB4 formation in human whole blood and reduces polymorphonuclear cell infiltration in mouse models. UCB-35440 inhibits histamine-stimulated bronchoconstriction and reduces skin inflammation in guinea pigs. UCB-35440 can be used for research on asthma and skin inflammation[1][2].
Molecular Weight:
576.09
Purity:
99.38
CAS Number:
[299460-62-1]
Formula:
C31H34ClN5O4
Target:
Histamine Receptor,Lipoxygenase
Application Notes:
MCE Product type: Reference compound
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