UR-1505 is a nuclear factor of activated T cells (NF-AT) inhibitor. UR-1505 can suppress CD3/CD28 induced T cell proliferation, increase p27KIP levels, and induce G1/S cell cycle arrest. UR-1505 can also inhibit the production of IL-5 and IFN-gamma in activated T cells. UR-1505 has immunomodulatory properties and can be used in the study of atopic dermatitis[1].
Molecular Weight:
286.15
Purity:
99.97
CAS Number:
[651331-92-9]
Formula:
C10H7F5O4
Target:
CD28,CD3,Interleukin Related,Nuclear Factor of activated T Cells (NFAT)
Application Notes:
MCE Product type: Reference compound
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