I-CBP112 (hydrochloride), CAS [[2147701-33-3]] Preis auf Anfrage

Product Overview

• Article Name: I-CBP112 (hydrochloride), CAS [[2147701-33-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-19541A
• Supplier Catalog Number: HY-19541A
• Alternative Catalog Number: MCE-HY-19541A-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

I-CBP112 hydrochloride is a selective inhibitor of CBP/P300 that directly binds their bromodomains (Kds = 142 and 625 nM, respectively). I-CBP112 significantly reduces the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells in a dose-dependent manner in vitro and in vivo. I-CBP112 increases the cytotoxic activity of BET bromodomain inhibitor JQ1 as well as doxorubicin[1].

Product Properties

• Molecular Weight: 505.05
• CAS Number: [2147701-33-3]
• Formula: C27H37ClN2O5
• Target: Epigenetic Reader Domain

Application Notes

• Application Notes: Reference compound