Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent[1]. Brusatol increases cellular apoptosis[2].
Molecular Weight:
520.53
Purity:
99.89
CAS Number:
[14907-98-3]
Formula:
C26H32O11
Target:
Apoptosis,Keap1-Nrf2
Application Notes:
MCE Product type: Natural Products
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