MM-401 is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia[1].
Molecular Weight:
586.73
CAS Number:
[1442106-10-6]
Formula:
C29H46N8O5
Target:
Apoptosis,WDR5
Application Notes:
Reference compound
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