Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).
Molecular Weight:
505.50
Purity:
99.87
CAS Number:
[1354799-87-3]
Formula:
C25H24FN7O4
Target:
JAK
Application Notes:
MCE Product type: Reference compound
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