OTS964 is an orally active, high affinity and selective TOPK inhibitor with an IC50 of 28 nM[1]. OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM[2].
Molecular Weight:
392.51
CAS Number:
[1338542-14-5]
Formula:
C23H24N2O2S
Target:
Apoptosis,CDK,TOPK
Application Notes:
Reference compound
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