NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway[1]. NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling[2].
Molecular Weight:
265.27
Purity:
99.43
CAS Number:
[803647-40-7]
Formula:
C12H15N3O4
Target:
MDM-2/p53
Application Notes:
Reference compound
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