Lecozotan (SRA-333) hydrochloride is an orally active and selective antagonist of 5-HT1A with a Ki of 4.5 nM for cloned human 5-HT1A receptor. Lecozotan hydrochloride enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. Lecozotan hydrochloride has the potential for mild-to-moderate Alzheimers disease (AD) research[1][2].
Molecular Weight:
520.02
Purity:
98.71
CAS Number:
[433282-68-9]
Formula:
C28H30ClN5O3
Target:
5-HT Receptor
Application Notes:
Reference compound
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