PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0.26 0.03 µM) over m-calpain (Ki = 5.33 0.77 µM). IC50 value: 0.26 0.03 µM (Ki, for µ-calpain), 5.33 0.77 µM (Ki, for m-calpain) [1] Target: calpain in vitro: The µ-calpain inhibitor PD 151746 decreases oxLDL-induced cytotoxicity. [2]
Molecular Weight:
237.25
Purity:
95.03
CAS Number:
[181765-30-0]
Formula:
C11H8FNO2S
Target:
Proteasome
Application Notes:
Reference compound
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