VU0357017 (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 µM). VU0357017 can be used for the research of Alzheimers disease and schizophrenia[1][2][3].
Molecular Weight:
333.43
CAS Number:
[1135681-23-0]
Formula:
C18H27N3O3
Target:
mAChR
Application Notes:
MCE Product type: Reference compound
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