I-BET282 is a pan-inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain-containing proteins. I-BET282 shows pIC50s ranging 6.4-7.7 for BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), and BRD4 (BD1/BD)[1].
Molecular Weight:
450.53
Purity:
98.90
CAS Number:
[1422554-34-4]
Formula:
C25H30N4O4
Target:
Epigenetic Reader Domain
Application Notes:
Reference compound
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