Indirubin-3-monoxime is a potent GSK-3beta inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively, Indirubin-3-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM.
Molecular Weight:
277.28
Purity:
99.80
CAS Number:
[160807-49-8]
Formula:
C16H11N3O2
Target:
CDK,GSK-3,Lipoxygenase
Application Notes:
MCE Product type: Reference compound
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