Avitinib (Abivertinib) is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib shows anticancer effects[1][2].
Molecular Weight:
487.53
Purity:
99.95
CAS Number:
[1557267-42-1]
Formula:
C26H26FN7O2
Target:
Apoptosis,Btk,EGFR
Application Notes:
MCE Product type: Reference compound
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