(Z)-4EGI-1 is the Z-isomer of 4EGI-1 and is an inhibitor of eIF4E/eIF4G interaction and of translation initiation. (Z)-4EGI-1 effectively binds to eIF4E with an IC50 of 43.5 µM and a Kd value of 8.74 µM. (Z)-4EGI-1 has anticancer activity[1][2].
Molecular Weight:
451.28
Purity:
98
CAS Number:
[901787-88-0]
Formula:
C18H12Cl2N4O4S
Target:
Eukaryotic Initiation Factor (eIF)
Application Notes:
MCE Product type: Reference compound
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