VRX-480773 is an efficient non-nucleoside reverse transcriptase inhibitor (NNRTI), used for HIV infection. VRX-480773 has high specificity for HIV-1, with an EC50 for wild-type HIV-1 being 0.14 nM. VRX-480773 does not inhibit HIV-2, HBV or HCV, and has no effect on human DNA polymerase alpha/beta. VRX-480773 retains inhibitory activity against Efavirenz (HY-10572) resistant strains, with EC50s mostly [1].
Molecular Weight:
592.92
CAS Number:
[878670-89-4]
Formula:
C23H19BrClN5O3S2
Target:
HIV,Reverse Transcriptase
Application Notes:
MCE Product type: Reference compound
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